Spinal machined bone allograft is defined as an allograft customized to precise dimensions to fill the gap between two bones. Demineralized bone matrix (DBM) refers to allogeneic bone that is pulverized and decalcified using hydrochloric acid. The process removes mineralized component and retains Type 1 collagen, osteoinductive growth factors, and non-collagenous proteins. DBM is biologically active as compared to mineralized bone grafts. Thereby, it helps in bone generation when applied as a bridge between two bones in the skeletal system.
New DBM offers High Osteoconductivity
Major product variants of spinal machined bone allograft are putty, gel, and putty with chips. Putty segment is anticipated to hold highest market share over the forecast period. DBM putty is intended for gaps and voids that are not intrinsic to stability of bone structure. It is used to treat defects or osseous defects in bones that occur during surgical procedures. Putty can be mixed with bone marrow or blood to provide moldable consistency.
To cater to rising demand for bone grafting, manufacturing companies are investing in R&D activities to develop advanced products. For instance, in February 2019, Medtronic launched demineralized bone matrix (DBM) in Japan. The newly introduced Grafton DBM is a bone graft substitute, bone graft extender, and bone void filler intended for gaps or voids in skeletal system. Its high osteoconductivity scores makes it preferable choice among surgeons and researchers for scientific studies. It can be used in orthopedic or reconstructive bone grafting procedures.
The global spinal machined bone allograft market is predicted to witness high volume by 2028, according to a report available on Million Insights. It is anticipated to exhibit a healthy CAGR over the forecast period 2013 to 2028. Growing prevalence of medical conditions such as disc displacement, scoliosis, and fracture is driving demand for advanced bone grafting techniques. Increasing number of spinal cord injuries owing to fatal road accidents is driving demand for effective bone grafts. In addition, availability of bone grafts in different shapes and sizes to fill voids in the skeletal system is promote spinal fusion surgeries. Moreover, supportive initiatives being taken by government and private organizations to improve healthcare facilities will drive the market over the forecast period.
Some of the leading companies operating in the spinal machined bone allograft market are Medtronic, Zimmer Biomet, Wright Medical Group, Stryker, and Hans Biomed.