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3D Cell Culture Market Analysis Report By Technology, By Application, By End Use, By Region And Segment Forecasts From 2021 To 2028

Report ID: MN17619102  |  Published: April 2021  |  No of Pages: 140
Format: Electronic (PDF)  |  Industry: Biotechnology


With reference to the report published, the global 3d cell culture market was prized by USD 1.5 billion in 2020. It is estimated to witness a 10.7% CAGR during the period of the forecast.


Since 3D cultures are able to intimately imitate a distinctive microstructural design and morphology of organs, they are extensively utilized in learning, which necessitates in vivo model arrangement, to scrutinize the possessions of external medicine, above body organs and tissues. The greater usefulness of the 3-dimensional form for the study, regarding Covid-19 as well as respiratory illness, is anticipated to propose considerable enlargement openings to the market for 3D cell culture.


A number of additional, most important factors, powering the expansion of the market comprise the presentation of new-fangled products and extensive function of 3D procedures, in biological investigation. Such as, a Canada headquartered Biotechnology Company, eNUVIO Inc., instigated EB-Plate, an entirely reusable microplate for 3D cell culture, in December 2020. This is estimated to decrease the expenditure of single-use plastics, augment the usefulness of 3-dimensional microplates, and boost the movement of no-waste in laboratories.

Effect of Covid-19

The innovators of the Biopharmaceuticals are at the front position of the individual reaction to the coronavirus pandemic. Large numbers of foremost biotech firms are in the center of competition, to explore the Sars-Cov-2 genome as well as make ready a practicable vaccine for the same. In contrast to the rapidity of the reaction to SARS/MERs and so forth, the biotech units are exploring SARs-Cov-2 at an unmatched speed and a substantial quantity of finances is being deposited in the R&D actions. By means of the numerous candidates involved in an experiment, the private, as well as public sectors, are expected to perform in unity, for the projected phase, in anticipation of a vaccine is developed for Covid-19.

Application Insight

In 2020, by retaining the biggest revenue share of 24.56%, the cancer segment led the 3d cell culture market. The usage of spheroids the same as model arrangement, throughout the improvement of anticancer treatment, impales R&D actions of this section. Furthermore, the utilization of 3-dimensional cellular models, designed for the analysis of cancer ecology in preclinical screening and test, is estimated to boost the revenue creation, within this section.

The stem cell research section is projected to record the highest CAGR, during the period of the forecast. An escalation in the function of the 3D cell culture stage for regenerative medication is likely to thrust the expansion of the sector.

Technology Insight

In 2020, the scaffold sourced technology retained the biggest revenue share in 3d cell culture market; it was more than 68.96%. The usage of hydrogels like scaffolds, in 3-dimensional cell culture sourced investigation, facilitate the integration of complicated mechanical as well as biochemical symbols, like a mirror of the natural extracellular medium. Furthermore, the instigation of new products and the rising necessity for the progression in hydrogels for giving a strong platform for learning cellular and human functioning is estimated to increase the progress of the 3d cell culture market, during the near future.

The rising alertness, in addition to the reputation of nanotechnology in the biomedical investigation, is expected to generate possible development scenarios for Nano fiber-sourced scaffolds, in this manner expanding the demand and sales for the scaffold sourced technology. The magnetic levitational assemblage of 3D tissue build is a rising and speedily developing label & scaffold-free method for tissue engineering. This is estimated to propel the scaffold-free sector by the highest CAGR, during the period of the forecast.

End-Use Insight

The pharmaceuticals and biotechnology business division created the major revenue share in 2020, it was above 46%. 3D cell cultures contain advantages, in the conditions of best nutrient and oxygen gradient, non-consistent contact of cells, inside a spheroid to medicine and sensible cell-to-cell connections, in contrast to 2D cell culture, to investigate medicine contestant. These things make 3D cell cultures superior and right for medicine invention and improvement, thus inspiring the demand.


The issues like the imperative requirement for additionally quick and precise analytical services and the rewards of 3D models above 2D models in giving thorough physiological information increases the progress of the diagnostic centers and hospitals sector. Furthermore, the existence of diagnostic centers, like Kiyatec, which are keenly occupied in offering 3D models for higher research, is anticipated to enhance the expansion of the sector growth, during the near future.

Industrialized laboratories and academic institutes are, furthermore, estimated to add to the growing share of 3d cell culture market. Training programs and workshops on 3D cell culture arrangement, offered by institutions are expected to force the requirement for 3D cell culture products & arrangements, for the duration of the forecast.

Regional Insight

In 2020, North America held more than 43% revenue share and ruled the global 3d cell culture market. Due to the availability of government along with the private financial support for the improvement of highly developed 3D cell culture form, excessive expenditure on healthcare, and the existence of a greater number of research institutes as well as universities, exploring a variety of stem cell-based methodology, the state will keep hold of its principal position, during the forecast period. The scientist of Mayo Clinic and Terasaki Institute, U.S., upgraded detectable hydrogels, which are able to be utilized for the check and manage the hemorrhage, in December 2020.

On the other hand, due to increasing funds by diverse global companies in the developing markets of this region, Asia Pacific is expected to be the speedily developing local market from 2021 to 2028.


The key players of the 3d cell culture market are concentrating on partnerships with new companies along with launching new products, to improve their attendance in the market. As, Corning, Inc. presented the Corning X-SERIES cell processing platform, intended for the application of gene and cell treatment, in June 2020. This platform provides automatic, quick, sterilized, and well-organized processing. The manufacturer of this product is Thermo Genesis Holdings, Inc. Furthermore, the company presented Corning Matrigel matrix-3D plates, in a similar month, for additionally reliable as well as suitable, set to utilize cell culture alternative to assist spheroid and organoid culture form.

Some of the companies for 3d cell culture market are:

    • Global Cell Solutions, Inc.
    • Tecan Trading AG
    • Lonza
    • Corning, Inc.
    • Promo Cell GmbH
    • Merck KGaA
    • InSphero
    • 3D Biotek LLC
    • Avantor Performance Materials, LLC
    • 3D Biomatrix
    • Greiner Bio One International GmbH
    • Thermo Fisher Scientific, Inc.

Report Scope

Report Attribute


The market size value in 2021

USD 1.74 billion

The revenue forecast in 2028

USD 3.48 billion

Growth rate

CAGR of 10.7% from 2021 to 2028

The base year for estimation


Historical data

2016 - 2019

Forecast period

2021 - 2028

Quantitative units

Revenue in USD million/billion and CAGR from 2021 to 2028

Report coverage

Revenue forecast, company ranking, competitive landscape, growth factors, and trends

Segments covered

Technology, application, end-use, region

Regional scope

North America; Europe; Asia Pacific; Latin America; Middle East & Africa

Country scope

U.S.; Canada; Germany; U.K.; Japan; China; Brazil; South Africa

Key companies profiled

Merck KGaA; Thermo Fisher Scientific, Inc.; PromoCell GmbH; Greiner Bio-One International GmbH; Corning, Inc.; 3D Biomatrix; Lonza; Avantor Performance Materials, LLC; Tecan Trading AG; 3D Biotek LLC; Global Cell Solutions, Inc.; InSphero

Customization scope

Free report customization (equivalent to 8 analysts working days) with purchase. Addition or alteration to country, regional & segment scope

Pricing and purchase options

Avail of customized purchase options to meet your exact research needs. 

Segments Covered in the Report

This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2016 to 2028. For the purpose of this study, Million Insight's has segmented the global 3D cell culture market report on the basis of technology, application, end-use, and region:

• Technology Outlook (Revenue, USD Million, 2016 - 2028)
    • Scaffold-based
        • Hydrogels
        • Polymeric Scaffolds
        • Micro-patterned Surface Microplates
        • Nanofiber-based Scaffolds
    • Scaffold-free
        • Hanging Drop Microplates
        • Microfluidic 3D Cell Culture
        • Spheroid Microplates with ULA coating
        • Magnetic Levitation & 3D Bioprinting
    • Bioreactors

• Application Outlook (Revenue, USD Million, 2016 - 2028)
    • Cancer
    • Tissue Engineering & Immunohistochemistry
    • Drug Development
    • Stem Cell Research
    • Others

• End-use Outlook (Revenue, USD Million, 2016 - 2028)
    • Biotechnology and Pharmaceutical Industries
    • Research Laboratories and Institutes
    • Hospitals and Diagnostic Centers
    • Others

• Regional Outlook (Revenue, USD Million, 2016 - 2028)
    • North America
        • U.S.
        • Canada
    • Europe
        • Germany
        • U.K.
    • The Asia Pacific
        • Japan
        • China
    • Latin America
        • Brazil
    • MEA
        • South Africa

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