The global Chromatography Resin Market is estimated to reach USD 2.86 billion by 2025, with a CAGR of 6.5% over the forecast period. Chromatography is a code of techniques used to purify as well as separate bimolecular substances such as proteins. Resin is the stationary matrices in the columns used in the aforementioned techniques. Chromatography resins are particularly used in multi-modal, ion-exchange, size exclusion, affinity, and hydrophobic interaction techniques. The widely used techniques are ion-exchange and affinity chromatography largely operated in pharmaceutical, food manufacturing, environmental analysis, and biotechnology.
Chromatography resins are available in three major types includes synthetic, inorganic, and natural media. Natural media polymers consist majorly of dextran, and agarose cellulose, and others. Industry prefers synthetic and natural type media over inorganic chromatography resins. In context with technology, ion-exchange chromatography experienced the largest consumption in the past few years. On the other hand, Protein A resins have witnessed the highest share of the market. Affinity chromatography had the key share in terms of revenue due to its higher selling cost integrated with affinity resins.
The key drivers for the chromatography resins could be the heavy demand for monoclonal antibodies owing to a heightened number of critical diseases concluding in types of therapeutics. Food analytics could be another major drivers for the market, due to its usage in nutritional and nutraceuticals chemistry. It deals with a major issue in the food industry by determining the adulteration and additives in the food. Pharmaceuticals and biotechnology are the major end-users for chromatography resins and are estimated to continue with higher numbers.
Industrial applications, such as environmental analysis and water treatment rely on these techniques. Various opportunities for the chromatography resins market could be in the academic usage of drug recovery and genetic engineering. However, government law and regulations integrated with the aforementioned applications could be a major restraint for the market shortly.
The growth in terms of therapeutic antibodies demand, increasing utilization of separation & purifying techniques in the food industry, and emerging R&D activities in biopharmaceuticals are some of the factors contributing to the chromatography resins industry growth. Monoclonal antibodies therapeutics are rapidly capturing importance with rising critical diseases across the world. The major factor restraining the global industry is the lack of skilled professionals. The adequate usage of chromatography equipment requires skill, knowledge, and expertise in different techniques. For example, the pharmaceutical industry is experiencing a lack of adequate professionals to work on chromatography equipment and their different techniques.
The key strategies opted by resin manufacturers include low-cost production with better properties for binding. The key manufacturer such Bio-Rad, Millipore, GE Life Sciences, and Tosoh Corporation concentrate on manufacturing resins at lower cost with high productivity to make a competitive edge. Affinity chromatography resins, including protein A-based resin, are considered to be the most expensive as compared to others. However, the expiry of the current patent would reduce the cost over the next seven years.
In the past few years, the leading manufacturers are adopting the strategy of advancement and introduction of new products with higher productivity. Therefore, manufacturers are now investing heavily into R & D activities. North America is estimated to hold a huge revenue share in the industry. The U.S. has witnessed the largest demand, particularly in the biopharmaceutical sector due to its heavy investment and improvement in the R & D. In this region, the growing opportunities for chromatography resins are primarily into Bio and pharmaceutical sectors. However, the Asia Pacific domestic market is estimated to witness significant growth over the forecast period owing to its maximum growth in context with consumption.
Some of the key players in the industry include Tosoh Corporation, Pall Corporations, Bio-Rad Labs, Life Technologies Crop, Repligen, and GE Healthcare Life Sciences, and others. The aforementioned manufacturers are revamping their strategies to gain a competitive edge by lowering their product prices with high productivity. Life technologies are projected to introduce ‘POROS’ resins in BPD (Bio-Pharmaceutical Development) and production week conference.
Purolite International Ltd. has introduced its plans for the development and improvement of bioseparation and purifying chromatography resins based on agarose media. This new product line is anticipated to cater to the rising demand in the biomolecules global market. Purolite has expanded a facility to reach the rising demand for its agarose Protein A resin, which is highly used for monoclonal antibodies purification. This would develop a resin with properties such as easy packaging solutions, high alkaline condition tolerance, long lifetime, and higher price as compared to other media.
Type Outlook (Revenue, USD Million, 2014 - 2025)
• Inorganic Media
Technique Outlook (Revenue, USD Million, 2014 - 2025)
• Ion Exchange
• Hydrophobic Interaction
• Size Exclusion
End-use industry Outlook (Revenue, USD Million, 2014 - 2025)
• Pharmaceutical & Biotechnology
• Food & Beverage
Regional Outlook (Revenue, USD Million, 2014 - 2025)
• North America
• the Asia Pacific
• South Korea
• South & Central America
• Middle East and Africa
Research Support Specialist, USA
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